Gordon Setter Health Studies/Research/Clinical Trial Participation Reference Chart (Updated June 2015)
This table is provided by GSCA Newsletter editor Sue Drum
and Published with permission
Health Issue/Research/Trial Link to additional information Dates/Contact info
Bladder or Prostate Cancer—Urine samples (with or without paired blood samples) are needed from dogs who have been diagnosed with transitional cell carcinoma of the bladder, urinary tract, or prostate; and from dogs diagnosed with adenocarcinoma of the prostate http://www.breenlab.org/recruitment.html

919-513-1466 / info@breen.org

Breen Lab at North Carolina State University
Blindness—If you have a Gordon Setter that is exhibiting some signs of blindness, but is rcd 4 CLEAR, samples (saliva swabs) needed. See issue #737 September 2015 Gordon Setter News, pg. 25, Animal Health Trust Calls for Samples

Bryan Mclaughlin bryan.mclaughlin@aht.org.uk

Telephone: +44 (0)1638 750659

Blood/Tissue Samples of Dogs in disease states

Collection of blood or tissue samples to explore canine genetic issues including patterns of genetic diversity between and within breeds and in disease states.
Broad Institute Blood/Tissue Samples

c/o Michele Perloski

Chemotherapy—Effects of Specially formulated diet on quality of life. (12/2014 News) Inclusion criteria: dogs > 1 yr with multicentric lymphoma (LSA) & grade 2 or higher mast cell tumors (MCT) that will be treated with standard chemotherapy protocols. This is a multi-center trial; add’l sites enrolling are: Vet. Medical Ctr of Central NY, Colonial Vet. Hosp., Ithaca, NY, VCA Animal Specialty Cntr, Yonkers, NY, Veterinary Cancer Cntr, Norwalk, CT, VCA South Paws Veterinary Specialists & Emergency Cntr, Fairfax, VA http://sites.tufts.edu/vetclinicaltrials/?qa_faqs=investigation-of-a-novel-diet-for-support-of-dogs-undergoing-chemotherapy-for-mast-cell-tumors-or-multicentric-lymphoma

Study info provided to us Nov. 2014; end date of study not known.

Tufts University; contact Kelly Reed, Oncology liaison at (508) 887-4682 or Diane Welsh, Clinical Trials Technician, clinicaltrials@tufts.edu


Blood and/or tissue samples are required for ongoing research. Suspected hemangiosarcomas—fresh (within 20 minutes of surgery or euthanasia) tumor plus blood
http://www.modianolab.org/studyInfo/studyInfo_index.shtml Sample require-ments and shipping information are provided in the text of the study info pg. Mitzi (612-626-6890, ext. 1, or lewel001@umn.edu) 24 hrs in advance of sending a sample & for tumor sample collection supplies)
Hemangiosarcoma (of the spleen)—Dose finding for a ligand targeted toxin to treat hemangiosarcoma. Dogs who are diagnosed with hemangiosarcoma (of the spleen) can qualify for this study. Once enrolled, the study covers study visits, study drugs, an PET-CT. In addition, the study covers up to $5,000 for staging diagnostics and chemotherapy treatments.

University of Minnesota Clinical Investigation Center:



for information on other clinical trials conducted by University of Minnesota.

(Study posted to this chart Nov. 2015; no trial close-dates referenced at that time).

Amber Winter, CVT, 612-624-1352 (alwinter@umn.edu) or Dr. Jaime Modiano, modiano@umn.ed
HOD (hypertrophic osteodystrophy)—Blood samples from any dog that has ever had HOD (developmental disease affecting rapidly growing lg dogs between 8 wks & 8 mths; affected puppies suffer joint pain resulting in lameness or refusal to stand or walk). http://www.vgl.ucdavis.edu/cghg/projects.php

UC Davis

Dr Noa Safra nsafra@ucdavis.edu or drnoasafra@gmail.com
Lymphoma, Conditionally Licensed Monoclonal Antibody + CCNU Chemo for Dogs with T-Cell Lymphoma (designed to assess the benefit of adding AT-005 to a single agent CCNU chemo protocol for dogs with intermediate to high grade T-cell lymphoma). Enrolling 60 dogs nationwide. http://www.animalci.com/trials/t-lab This study can close at anytime depending on how quickly the slots fill. Link to the trial provides list of veterinary oncology centers offering this clinical trial.
Lymphoma & other hematologic malignancies (provide bone marrow transplants (hematopoietic stem cell therapy)—collaboration with a group of veterinary oncologists around the country who are now providing bone marrow transplants.


Additional locations:

—Veterinary Specialty Hosp. in San Diego, CA, 858-875-7500, website: http://www.vshsd.com/

—North Carolina State Veterinary Hosp. in Raleigh, NC, 919-513-6690, website: http://www.cvm.ncsu.edu/vhc/tc/clinical_services/onco/index.html

—VCA West Los Angeles Animal Hosp., Los Angeles, CA, 310-473-2951,  http://www.vcaspecialtyvets.com/west-los-angeles/our-services/oncology/bone-marrow-transplant

Dr. Edmund Sullivan/Dr. Theresa Westfall; Bellingham Veterinary

720 Virginia Street Bellingham, WA 98225; (360) 734-0720

See column to the left for additional locations now performing this treatment.
Mast cell tumors—Blood or stored tissue samples are needed from any case of MST that is/was Grade 2 within the past 3 years. http://www.breenlab.org/recruitment.html

919-513-1466 / info@breen.org

Breen Lab at North Carolina State University
Tumors—“Tumor Paint” study (July 2015 News)—Evaluate the ability to view not only the tumor, but sur-rounding cancer cells during surgery & better understand how Tumor Paint binds to soft tissue sarcomas, mammary tumors, lung tumors and brain tumors. Enrolled dogs need to a) have a diagnosed, malignant, solid tumor that can be surgically removed; b) have life expectancy > six weeks; c) no evidence of metastasis (beyond lymph nodes); d) not-pregnant nor lactating; e) deemed healthy enough to under-go anesthesia/surgery. Need to spend 8 hrs at the WSU-VTH on injection day; may be required to have blood samples taken at least 3 times after Tumor Paint injection. http://vcs.vetmed.wsu.edu/research/clinical-studies/tumor-paint  Enrolled dogs will receive state of art therapy to remove solid tumors. Owners responsible for costs associated with diagnosis of dog's cancer & surgery/anesthesia costs beyond the $ credited by the study. Owners may also be responsible for the costs of add’l hospitalization/meds/procedures associated with unforeseen complications. Upon study completion owners will receive a $1,000 credit towards their pet’s bill.

Valorie Wiss, Clinical Studies Coordinator; Office: 509-335-0798

Cell: 509-432-5345 /vwiss@vetmed.wsu.edu

Dr. Janean Fidel, Clinic: 509-335-0711 / jfidel@vetmed.wsu.edu